Recombinant Human Interleukin-2/IL-2 (C-6His-Avi) Biotinylated

Sizes: 20μg, 100μg

Catalogue Numbers: PKSH033973-20, PKSH033973-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: Interleukin-2; IL-2

Target Symptom: Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

Research Area: immunology

Conjugation: Biotinylated

Target Species: Human

Expression Host: HEK293 Cells

Application: Cell culture

Fusion Tag: C-6His-Avi

UNIProt ID: P60568

Accession: P60568

Background: Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

Activity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.2 ng/mL.

Sequence: Ala21-Thr153

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 18.3 kDa

Observed MW: 16-18 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only