Recombinant Human Interleukin-21/IL-21 Protein (Active)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032631-10, PKSH032631-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Interleukin-21; IL-21

Target Symptom: Interleukin-21; IL-21; Za11; IL21

Research Area: Cancer; immunology

Target Species: Human

Expression Host: E.coli

Application: ELISA

Fusion Tag: None

UNIProt ID: Q9HBE4

Accession: Q9HBE4

Background: IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.

Activity: Immobilized Human IL-21 at 10μg/ml(100 μl/well) can bind Human IL-2RG-Fc(Cat: PKSH033410).

Sequence: Gln23-Ser155

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 15.6 kDa

Observed MW: 16 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only