PKC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20755-50, RA20755-100

Citations, Manuals and MSDS Available upon request.

Background: protein kinase C alpha (PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. [provided by RefSeq, Jul 2

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha; PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta; PRKCD; Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta; PRKCE; PKCE; Protein kinase

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5578/5579/5580/5581/5582/5583/5588/5590

Protein MW (KDa): 67-83kD (α 76，δ/β 77，γ 78, θ/ε83 , ζ 67)

SWISS: P17252/P05771/Q05655/Q02156/P05129/P24723/Q04759/Q05513

Source: Rabbit

Research Use Only