Phospho-p90Rsk/RSK1/RPS6KA1-T359/S363 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS79398-50, BS79398-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15418

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB,1:500 - 1:2000

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of A431 cells, using Phospho-p90Rsk/RSK1/RPS6KA1-T359/S363 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.

Bioworld Molecular Weight: 83kDa

Specificity: Phosphorylated

Alternative Name: HU-1; MAPKAPK1A; RSK; RSK1; p90Rsk; RPS6KA1

Immunogen: A synthetic phosphorylated peptide around T359 & S363 of human p90Rsk/RSK1/RPS6KA1(NP_002944.2).

Conjugate: Unconjugated

Modification: Phosphorylated