RECQ5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13430-50, ES13430-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human RECQ5 AA range: 647-697

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 9400

Human SWISS Prot NO: O94762

Subcellular Location: [Isoform Beta]: Nucleus, nucleoplasm. Nucleus. Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks. Re-localizes from the nucleolus into the nucleus after replicative stress and significantly associates with WRN during S-phase (PubMed:23180761).; [Isoform Alpha]: Cytoplasm.; [Isoform Gamma]: Cytoplasm.

Research Use Only